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Product Development Chemist required, based in Cheshire West on a permanent basis. Degree required in Chemistry, with proven industrial experience of synthetic/formulation chemistry. Mineral extraction knowledge experience is desirable but not essential, as is a PhD in Synthetic Chemistry.
Title: Product Development Chemist
Location: Cheshire West
Salary: £40,000 - £45,000 per annum (dependent on experience)
Term: Permanent
SRG are working with a highly innovative company who develop speciality chemicals for a wide range of downstream industries - including agrochemicals, personal care and mineral extraction. They are now looking for a Product Development Chemist to evaluate the performance and properties of their synthesised chemical additives in formulations used for mineral extraction. This brand-new role will involve formulation and synthesis work of both new and existing products, as well as testing them to meet performance and stability targets. This role will suit candidates with proven industrial experience of synthetic/formulation chemistry within a range of different markets including personal care, household, janitorial, agrochemical, foaming products and mineral extraction. Candidates that hold a PhD with industrial experience are also encouraged to apply.
Benefits: You will join a small team in a larger, diverse & dynamic department - with lots of opportunities to learn from experienced scientists in varied disciplines. An excellent environment to build a career in. 37.5 hours, Mon-Fri, flexible start & finish times. Excellent company pension & annual bonus potential, private healthcare. 25 days holiday + 8 bank holidays.
Role / Description
Requirements
If you would like to apply for this position, please use the link provided. Alternatively please email a copy of your CV to For more information regarding this position or any others, please call Chris on 0161 526 1898. If you have a scientific background and this position is not relevant / suitable for you, please feel free to get in touch or visit www.srgtalent.com to view our other vacancies.
SRG is the UK's number one recruitment company specialising in the scientific, engineering, clinical, pharmaceutical, food/FMCG, energy & renewables, biotech, chemical and medical device sectors. As scientists ourselves, our specialist sector knowledge and our passion are second to none. It's this combination that makes us different. We're committed to providing outstanding temporary, contract and permanent career opportunities of all levels for our candidates and a comprehensive range of expert strategic recruitment services for our clients.
Keywords: formulation, surfactant, laboratory, chemistry, cosmetic science, degree, graduate, chemical, agrochemical, wet chemistry, bench chemistry, testing, viscosity, rheology, stability, melting point, dispersion, suspension, particle size, Malvern, Brookfield, PhD, synthetic chemistry, synthesis, mineral extraction, ores, minerals, testing, analysis.
Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.
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Job Description
Our company is currently seeking a subject matter expert in packaging design, development and qualification in support of combination product images ranging from pre-filled syringes, inhalers, auto-injectors and other complex drug delivery systems. This position will be part of our company's Device Development department responsible for combination product and process development for all of our company's drugs, biologics and vaccines requiring delivery devices. The scope of the role includes design and qualification of the primary packaging interface of the drug delivery device in support of clinical product supply. Additionally, the role includes the design and optimization of trays, bulk packaging, and other interfaces for device components in support of shipping and feeding for assembly operations. The intermediate and final combination product clinical package will have line-of-sight to the commercial configuration when feasible. In these situations, the early development and clinical packaging designs must include commercial design and manufacturability considerations.
This role will partner with the working groups within the department and across the organization to design and develop the packaging interface for the drug delivery device system with intimate knowledge of the delivery device design in support of clinical supply, distribution and use. Testing of the packaging interface will be conducted (or coordinated with external facilities) to assess the suitability of the design through phase-appropriate evaluations. The successful candidate will need to collaborate effectively with both the global clinical supply operations team as well as packaging commercialization and technology teams to ensure robust machinability and shipping/distribution performance is built into the packaging design. Deep knowledge of shipping study standards and guidance, as well as medical device design controls, device risk management, design verification and human factors considerations is critical.
Responsibilities
Serve as a subject matter expert in packaging design and evaluation to a diverse team of engineering professionals in support of clinical and commercial product development
Collaborate highly effectively with internal partner groups including drug product development, analytical development, manufacturing, technical operations, packaging, quality, regulatory affairs, and clinical supplies to deliver robust combination product manufacturing processes and product quality control strategies
Establish, develop, and maintain strong business relationships with external packaging design and component suppliers
Actively participate on Device Working Groups to extract technical requirements and development timelines for all combination products in the company'sportfolio to inform on packaging design and development strategies
Actively represent Device Development externally as a member of professional committees and at relevant conferences/consortia across the industry
Required Experience & Skills
B.S. in Packaging, Mechanical, Biomedical, or related Engineering discipline
15+ years of experience in the medical device, pharmaceutical and/or combination product industry
Experience partnering with packaging development and equipment suppliers
Experience partnering with packaging test labs
Prior direct responsibility for designing, developing and evaluating packaging solutions for drug-device combination products or medical devices
Good Manufacturing Practices (GMP)
ASTM D3475, ISO 11607, ISO 15378. ISO 18601 ISO 9001, General Simulation Performance Tests ISTA 3A, European Committee for Standardization (CEN), Notified body requirements and relevant standards
Experience in authoring relevant packaging related content of clinical and registrational regulatory submissions
Preferred Experience & Skills
Experience in product design, concepting and prototyping
Experience with medical device development including an understanding of 21 CFR Part 4, Design Controls (21 CFR 820.30), Purchasing Controls (21 CFR 820.50), Corrective and Preventative Actions (21 CFR 820.100), Production and Process Controls (21 CFR 211 Subpart F), as well as ISO 13485, ISO 14971, and EU 2017/745 (MDR)
Excellent problem-solving capabilities
Strong decision-making skills, weighing advantages, disadvantages, and business impact for rapid decisions
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.
Expected salary range:
$149,400.00 - $235,100.00Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
10%Flexible Work Arrangements:
Not ApplicableShift:
1st - DayValid Driving License:
NoHazardous Material(s):
n/aOfficial account of Jobstore.
Job Description
Vaccine Drug Product Development, a part of our company's Research Laboratories in West Point, PA, is seeking a Scientist or Engineer to join our department. The successful candidate will work as part of a team responsible for the design and development of vaccine drug products from preclinical through Phase III with a line of sight to commercialization. Primary responsibilities include the design, execution, and documentation of lab activities supporting formulation of novel vaccine antigens (e.g., RNA, live virus vaccines, subunit etc.), adjuvants, and delivery systems.
Experience with skills related to drug product development desirable (formulation, filtration, analytical/biochemical/biophysical characterization, process development, etc.) and a motivation to learn new techniques while working in a laboratory setting is required. The successful candidate will be expected to work in a hands-on and dynamic laboratory environment while also working collaboratively within cross-functional teams responsible for developing the next generation of vaccine drug products at our company.
Main Responsibilities:
The design, execution and documentation of lab-based activities to design, develop, characterize and optimize vaccine formulations.
Minimum Education Requirement:
B.S. or M.S. in Chemistry, Biology, Biochemistry, Biophysics, Chemical/Biochemical engineering, Virology, or related discipline with 0-5 years of relevant experience
Required Experience and Skills:
Experience designing, executing, and critically interpreting results from experiments
Excellent communication, writing and collaboration skills
Strong organizational and technical problem-solving abilities
Ability to work in a dynamic team environment
Desired Experience and Skills:
Experience with analytical characterization of biotherapeutics including biochemistry, particle size analysis and other biophysical methodologies
Formulation development experience with biotherapeutics including carbohydrate, protein and/or live viral vaccines for parenteral administration
Demonstrated proficiency in aseptic technique
Understanding of the drug product manufacturing process and scale-up considerations
Experience with preparation and/or manufacturing of safety assessment or clinical supplies
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
No relocationVISA Sponsorship:
NoTravel Requirements:
10%Flexible Work Arrangements:
Shift:
1st - DayValid Driving License:
NoHazardous Material(s):
N/AOfficial account of Jobstore.
Collaboration drives Nordson’s success as a market leader in Industrial Precision Solutions and Advanced Technology. Our employees thrive in an environment where we help each other reach our personal best and enable our company to continuously improve and grow, and our customers to succeed. You will find Nordson employees sharing our success by giving back in the communities around the world where we live and work.
Job Summary
Contribute the design and develop innovative products and custom components for the healthcare industry in line with Nordson MEDICAL strategic goals and product roadmap. Learn and support the activities and projects of product management department and Engineers within the guidelines of company policies and product development procedures.
Essential Job Duties and Responsibilities
Non-Essential Duties & Responsibilities:
Perform other duties as assigned, verbal and written.
Education and Experience Requirements
Preferred Skills and Abilities
Computer Skills:
Competencies:
Results Oriented/Accountability
Computer Skills
Mechanical Skills
Goal Achievement & Objective Setting
Analysis/Analytical Skills
Attention to Detail
Multi-Tasking
Initiative
Judgment
Dependability/Reliability
Accuracy
Critical Thinking Skill/Reasoning
Problem Solving
Planning & Organizing
Time Management Skills
Follow-Through
Safety Awareness
Working Conditions and Physical Demands
While performing the duties of this job, the employee is regularly required to sit; use fingers to handle or feel and talk or hear.
The employee is frequently required to stand; walk and reach with hands and arms. The employee is occasionally required to
climb or balance; stoop, kneel or crouch. The employee must occasionally lift and/or move up to 50 pounds. Specific vision
abilities required by this job include close vision, color vision, depth perception and the ability to adjust focus. The ability to read
and interpret details on a computer screen, drawing, or a physical part often in multiple colors is required. Work in a
manufacturing/tool room environment (i.e. coolants, metal chips, noise up to 80 db etc.), and manufacturing cells where plastic injection parts are produced (i.e. plastic dust, pneumatic pick & place robots, material grinders, etc.). May fluctuate work time from 90% at a computer work station to 90% in a lab or production environment. Requires frequent periods of time working in injection molding, assembly and tool room areas.
Office environment. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.
Travel Required
None Minimal Estimated __%
Equal Opportunity Statement
Nordson Corporation provides equal employment opportunity to all applicants and employees. No person is to be discriminated against in any aspect of the employment relationship due to race, religion, color, sex, age, national origin, ancestry, disability, sexual orientation, gender identity, genetic information, citizenship status, marital status, pregnancy, veteran status or any other status protected by applicable federal, state, or local law.
All employment offers are contingent upon successful completion of our pre-employment drug screening and background/criminal check, consistent with applicable laws.
Nordson Corporation provides equal employment opportunity to all applicants and employees. No person is to be discriminated against in any aspect of the employment relationship due to race, religion, color, sex, age, national origin, ancestry, disability, sexual orientation, gender identity, genetic information, citizenship status, marital status, pregnancy, veteran status or any other status protected by applicable federal, state, or local law. All employment offers are contingent upon successful completion of our pre-employment drug screening and background/criminal check, consistent with applicable laws.Third party recruiters and agencies should not contact employees of Nordson or its subsidiaries directly. Any resumes sent to a hiring manager or submitted to Nordson employees are considered unsolicited and property of Nordson. Nordson will not pay a placement fee unless the agency or recruiter has a signed contract with Nordson’s Human Resources department in advance of submitting a candidate for consideration. Verbal and written approvals will not be considered a valid contract for service.Official account of Jobstore.
Position Summary
Samsung Ads is an intuitive audience platform that delivers meaningful experiences reaching the right audience across Smart TV, mobile, and desktop. With more than 50M Smart TVs, 200M connected devices, and the most extensive first-party data set powered by ACR, we help marketers reach targets and enhance experiences that span digital landscapes. The business has grown 10x since 2015.Role and Responsibilities
Responsibilities
Lead the buildout, launch, and adoption of new Audience Intelligence, ML, and performance advertising solutions while concurrently launching enhancements/improvements to existing features.
Work cross-functionally with global engineering, design, product marketing, and sales and collaboratively with other product teams to gather requirements and identify opportunities for improved revenue and user experience.
Support the vision and strategy for the overall products within the Product Area.
Communicate product strategy, plans, and progress to stakeholders
Stay on top of trends in the advertising industry
Define metrics and KPIs you will use to measure the success of your products.
Skills and Qualifications
Experience
Eight or more years of experience. This can include Product Management/Technical Product Management with at least three of these years in Digital Advertising/AdTech
Bachelors Degree Required, Masters Preferred
Track record of end-to-end product delivery and demonstrate the impact of the products you have shipped
Experience applying machine learning in product development
Experience owning product and roadmap strategy
Experience in Agile product development
Understanding existing and competitive performance advertising solutions (DSPs, publishers, etc.)
Comfortable dealing with data. Experience with SQL and data processing/data warehouses a plus
Comfortable balancing concurrent projects and managing tradeoffs of a product
Understanding and experience building consumer-facing AdTech products is a plus.
Bachelor’s Degree Required, Masters Preferred
Excellent verbal and written communication skills
CALIFORNIA ONLY
Compensation for this role is expected to be between $170,000 and $190,000. Actual pay will be determined considering factors such as relevant skills and experience, and comparison to other employees in the role.
#LI-YRC
#Hybrid
* Please visit Samsung membership to see Privacy Policy, which defaults according to your location. You can change Country/Language at the bottom of the page. If you are European Economic Resident, please click here.
At Samsung, we believe that innovation and growth are driven by an inclusive culture and a diverse workforce. We aim to create a global team where everyone belongs and has equal opportunities, inspiring our talent to be their true selves. Together, we are building a better tomorrow for our customers, partners, and communities.
* Samsung Electronics America, Inc. and its subsidiaries are committed to employing a diverse workforce, and provide Equal Employment Opportunity for all individuals regardless of race, color, religion, gender, age, national origin, marital status, sexual orientation, gender identity, status as a protected veteran, genetic information, status as a qualified individual with a disability, or any other characteristic protected by law.
Reasonable Accommodations for Qualified Individuals with Disabilities During the Application Process
Samsung Electronics America is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application process. If you have a disability and require a reasonable accommodation in order to participate in the application process, please contact our Reasonable Accommodation Team (855-557-3247) or SEA_Accommodations_Ext@sea.samsung.com for assistance. This number is for accommodation requests only and is not intended for general employment inquiries.
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You're an original. So are we.
For more than 160 years, we've used the strength of our brands to lead with our values and make an outsized impact on the world. We employ more than 15,000 people globally to support our great brands: Levi's®, Dockers®, Denizen®, Signature by Levi Strauss & Co.™ and Beyond Yoga.
This summer you could work for one of Levi Strauss & Co.’s iconic brands! Our Fostering Influential Talent (F.I.T.) Internship Program give students real-world exposure to one of the world’s leading fashion and apparel companies. Our 10-week Summer F.I.T. Program is based at a LS&Co. office and is the perfect way to gain work experience in the core of the organization, while learning what a career at LS&Co. might have in store for you.
In addition to daily responsibilities, all F.I.T. Interns will participate in summer project in their department to support an important business initiative and work with various areas of our business and our brands. Leadership seminars and career exploration learning series connect our interns to our leaders and provide exposure to different career paths internally. Intern performance will be assessed over the Summer and could potentially lead to a full-time offer upon graduation.
NOTICE: For this role, we presently are seeking candidates who will not require Company visa sponsorship for the internship program, or for a potential follow-up offer of regular employment. Candidates who require such visa sponsorship will not be considered. For any roles working remotely, the work must also be performed inside the United States, not in a foreign country.
About the Role:
Build and support, important relationships (with peers, Supply Chain Services, Global Sourcing, and suppliers) grounded in clear goals, accountabilities, and respect
Use skills, capabilities to support the assigned business
Provide accurate reporting on all metrics and timeline processes (such as sample status) with input from important internal and external supply chain partners; maintain clear accountabilities, deliverables and measures
Follow all compliance standards relating to all product quality, product safety, and Terms of Engagement (TOE) requirements
Support the Product Development & Sourcing team in achieving aesthetic and cost targets through the execution of products, from concept to manufacturing-ready, while meeting all “Go To Market” milestones
Requirements:
High school diploma or GED
Must be enrolled in an accredited undergraduate, associate program or graduate program
Expected Graduation date Spring 2025
Eligible to work in the U.S. or Canada (based on role location) and provide proof of work authorization
Experience with apparel industry and product knowledge (preferred)
Additional Information:
Salary: $30/Hour for undergraduate
Relocation: Travel and housing assistance will be provided if you need to relocate for the summer
Paid U.S. and Canada Corporate holidays
Product discount of 60% off regular-price Levi’s merchandise
Levi Strauss & Co. is committed to equal employment opportunity, affirmative action, and recruiting and maintaining a workforce that welcomes and respects people from diverse backgrounds while enabling our employees to make an impact. We value the unique combination of talents, experiences, and perspectives of each employee, making our collective success possible.
#LI-Onsite
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Job Description
Position Description:
Associate Principal Scientist
The Sterile and Specialty Products (SSP) group is responsible for developing non-oral dosage forms (injections, implants, inhaled, ocular) for small, intermediate, and large molecules from preclinical toxicology studies to commercialization. Our development teams ensure robust composition, primary packaging/device, and process selection through deep fundamental understanding and characterization such that the process is scalable without compromising stability, safety, efficacy, and delivery. During development, we leverage smart experimental design, cutting edge analytical tools, and predictive approaches to inform molecule, formulation and process selection. In summary, our team enables the translation of preclinical candidates into non-oral drug products.
Our team is looking for a candidate for the position of Associate Principal Scientist (R4) supporting the Biologics formulation team within Sterile and Specialty Products.
Primary duties:
Lead/ contribute towards the new, innovative approaches for biologics sterile product development through the generation of experimental designs, execution of experimental plans and data analysis.
Support both early and late-stage development candidates, including screening and development of robust drug product composition, scalable process, primary packaging, compatibility characterization for processing and administration, and supporting regulatory filings.
Build deep fundamental knowledge around the drug product to ensure completion of key milestones and laboratory / regulatory documentation.
Active strategic and technical leadership on program development teams, interfacing with key stakeholders, and collaborating across functions to drive defined milestones will be required.
Responsible for leading and championing organizational strategic and innovation objectives aligned with organizational goals.
Be willing to take initiative, motivated to excel, have a strong technical background, have excellent communication and interpersonal skills, ability to multi-task, mentor scientists, and a strong desire to learn and contribute.
Leads project activities at external manufacturing sites including tech transfers.
Enhance our Company's professional image and competitive advantage through patents, presentations, publications and professional activities and advance areas such as science and technology development, technical and business strategic improvements, business process innovations.
Maintain awareness of relevant new and current technologies, capabilities, and effectively share this knowledge with others.
Position Qualifications:
Education Minimum Requirement:
Ph.D. in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline with a minimum of 4 years relevant industry experience.
B.S. or M.S. degree in Engineering, Pharmaceutical Sciences or related discipline with minimum of 8 years relevant industrial experience.
Required Experience and Skills:
Experienced in biologics process development and characterization particularly for late-stage programs.
Capable of leading formulation development activities in matrix team environments to define a robust formulation and manufacturing process.
Recognized as a technical expert and scientific contributor with proven ability to identify and develop innovative ideas.
Has broad knowledge of formulation science and in depth-knowledge in multiple areas, including core understanding of the drug development process.
Track record of working effectively with team-members of diverse skill sets and backgrounds.
Strong verbal and written communication skills
The candidate should have a strong track record in product development/ regulatory filing/ drug delivery/ complex formulation and process development/ characterization reflected through industry experience and external publications/ patent.
Preferred Experience and Skills:
Prior experience leading development projects at an enterprise level
Capable of mentoring individuals in a peer-to-peer fashion and as a technical mentor
Recognized as a subject matter expert in at least one drug delivery and/or manufacturing technology.
Demonstrated ability to identify, fundamentally characterize and address manufacturing challenges through the development and optimization of novel production technologies.
Desire to build new capabilities through the evaluation of new technologies and hands-on optimization of existing technologies.
Prior experience with process scales up, modeling, regulatory filings and/or driving key capability evaluation/ build would be highly preferred.
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.
Expected salary range:
$118,640.00 - $186,800.00Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
No Travel RequiredFlexible Work Arrangements:
Shift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
naOfficial account of Jobstore.
Job Description
The Continuous & Expression Technologies Group (CET) within the Process Research & Development, Enabling Technologies department is seeking motivated and creative individuals who are looking for an opportunity to positively impact our company’s manufacturing platforms, while actively supporting drug development in the biologics, vaccine and small molecule spaces. Specifically, CET is seeking Scientists specializing in bioprocessing technologies for vaccine candidates encompassing multiple therapeutic classes – including virus-like particles, nucleic acid vaccines, conjugates, and live/attenuated viruses - at our site in West Point, PA.
The CET group is tasked with identifying, developing, and deploying continuous manufacturing tools and methodologies aimed at improving production processes being developed for molecules in the company’s drug candidate pipeline. Knowledge of intensified unit operations such as multi-column chromatography, single-pass ultrafiltration and in-line diafiltration in addition to applied knowledge of hardware/software integration, process automation systems, and process analytical technologies (PAT) are valued skills within the group. Demonstrated expertise in vaccines or biologics process development, whether upstream, downstream or both, is particularly desirable.
As a member of the CET Group, the applicant will serve as an individual scientific contributor as part of a team responsible for the evaluation of enabling technologies. The candidate is also expected to carry out collaborative research supporting implementation of these methodologies which involves conceiving, designing, and driving vaccine process development experiments. The chosen candidate should also have excellent interpersonal, communication and collaboration skills and maintain a focused attention on laboratory safety for his- or her-self and the team.
Responsibilities include but are not limited to:
Contribute to the development of next generation vaccine manufacturing and process development platforms.
Design and conduct experiments for individual vaccine unit operations using relevant operational parameters and analytical inputs.
Integrate unit operations both physically and with relevant process control and monitoring platforms for concurrent operations.
Contribute to a safe and compliant laboratory work environment.
Education Minimum Requirement:
BS with 2+ years of experience, or MS with relevant academic or thesis experience in chemical engineering, biological sciences, microbiology, or related field (with an expected graduation no later than June 2024)
Required Experience and Skills:
Experience in the preparative bioprocessing of proteins, viruses, VLPs, mRNA and/or large biological molecules
Technical background in bioprocess techniques such as chromatography and membrane operations, and common biochemical analytical techniques
Well-developed organizational, record-keeping, and problem-solving skills
Experience with large molecule biophysical properties, and general biological laboratory practices.
Preferred Experience and Skills:
Experience with statistical data analysis tools and design of experiments
Experience with chromatography systems (e.g. AKTA)
Experience with aseptic technique.
Familiarity with GxP principles and regulations
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
#EBRG
#vetjob
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
NoTravel Requirements:
10%Flexible Work Arrangements:
Not ApplicableShift:
1st - DayValid Driving License:
NoHazardous Material(s):
N/AOfficial account of Jobstore.
Graco manufactures and markets premium equipment to move, measure, control, dispense and spray a wide variety of fluid and powder materials. What does that mean? Well, we pump peanut butter into your jar, and the oil in your car. We glue the soles of your shoes, the glass in your windows and the screen on your phone. We spray the finish on your vehicle, coatings on your pills, the paint on your house and texture on your walls. Graco is part of your daily life.
Job Purpose:
The New Product Development Manager is responsible for supporting the Corporate Procurement Department as a key member of the New Product Development team. The New Product Development Manager manages all strategic and tactical procurement related tasks from development to production as needed to meet product launch requirements. They will work closely with commodity teams, design teams, production teams, quality and suppliers to control product costs, time lines, and product performance to meet project milestones while maintaining the strategic direction of the corporate commodities teams.
Essential Duties:
Strategically identify and manage the sourcing and procurement of components identified by multiple divisional New Product Development design teams for active and future projects to align with the divisional design engineering growth goals.
Drive the investigation and qualification of new suppliers due to project needs or technological advances outside of our current supply base capabilities while collaborating with the commodity team(s) and Supplier Quality Engineers.
Expertise in component specifications related to materials being sourced and the processes being used to manufacture those components. Drive, while collaborating with the commodity teams, to select the best manufacturing processes and associated preferred suppliers resulting in a component that meets all organizational needs.
Analyze, identify, and propose mitigations to reduce both short-term and lifecycle quality and material availability risks for new product bills of material.
Collaborate with design, manufacturing, and commodity teams to identify processing opportunities outside the current design that offer cost reductions, lead time reductions, or product development timeline improvements to better meet key project goals.
Coordinate and manage project related engineering requisitions, prototyping requisitions, tooling requisitions, and field test parts. Communicate all tooling lead times, drawing change impacts, and status of all parts (tooled or standard) to the project teams.
Responsible for strategic and tactical purchasing input throughout all phases of a project including supplier selection, tooling purchases, and first article completion to qualify product to meet key project milestones.
Accountable for completion of tactical tasks including quoting, communicating drawing changes and specification revisions to the supplier, PO maintenance, delivery status, expediting, and loading costs into Oracle. Strategically develop plans to mitigate any risks that may negatively impact project milestones.
Drive commodity management engagement with engineering and manufacturing to reduce product development timelines based on phase gate needs.
Drive print reviews of supplied parts between engineering, manufacturing, supplier quality engineering, and suppliers to define critical part requirements.
Identify and document cost reduction opportunities and communicate them to the respective commodity team(s).
Promote strategic and continuous improvement in New Product Development processes and practices related to the procurement of Graco goods.
Create and assist in the internal and external education and training necessary to achieve quality procured product
Work with suppliers to obtain compliance certification
Adhere to and develop improvements for Corporate Procurement related procedures and work instructions
Provide general troubleshooting for day-to-day issues
Perform other duties as assigned.
Position Requirements:
Education:
Bachelor’s degree; preferably in Engineering, Operations/Supply Chain/Materials Management, or equivalent
Experience:
Minimum of 5 years purchasing/supply chain management experience with demonstrated capabilities
Strong knowledge base and experience in multiple industrial commodities.
Strong communication skills to support necessary interaction with suppliers, internal customers, support groups, engineers, and management
Collaborative and persuasive team player
Motivated self-starter who can work independently with minimal supervision
Must be flexible in assignments and be proficient in managing multiple priorities
Strong understanding and interpretation of detailed blueprints, specifications, and tolerances
Strong computer skills (Excel, MS Word, PowerPoint, web browsers)
Occasional travel required
Desirable:
Project Management experience preferred within the New Product Development capacity
Manufacturing Experience
MBA
ISM, CPSM, APICS or actively pursuing certification
Work Environment:
Full time, minimum of 40 hours per week
Monday – Friday
Professional office environment
#LI-AI1
Power to Be
At Graco, the Power to Be means providing the support, resources and freedom to pave your own way. Bring your unique attributes to the table, along with a commitment to being your best self, and you can be a part of a culture that rewards effort, celebrates uniqueness, and gives you the tools you need to succeed and become your best, fullest self along the way. Our culture empowers employees to chart their own career path. Our managers provide support and opportunities while offering freedom for employees to find their own Power to Be. Whether you decide to move up within the same department or expand to another cross-functional group, you will gain the well-rounded experience to succeed on your own terms.
Graco has excellent opportunities available to individuals who want to be part of a fast-moving, growing company that is committed to quality, innovation and solving fluid handling problems for our customers. Graco is proud to be named a Best Place to Work by Fortune Magazine in 2016, 2018, 2019, 2021 & 2022. Graco offers attractive compensation, benefits and career development opportunities. Graco’s comprehensive benefits include medical, dental, stock purchase plan, 401(k), tuition reimbursement and more.
Our company uses E-Verify to confirm the employment and eligibility of all newly hired employees. To learn more about E-Verify, including your rights and responsibilities, please visit www.dhs.gov/E-Verify.
Proven Quality. Leading Technology. Launch your career with Graco!
Official account of Jobstore.
Job Description
Vaccine Drug Product Development (VDPD), a part of our company's Research Laboratories, is seeking a Principal Scientist to join our department in West Point, PA. Our mission is to develop novel vaccine drug products that will profoundly improve global human health—directly building from our company's 50+ year legacy as pioneers in the discovery, development, and manufacturing of novel vaccines to eliminate disease. Our department is responsible for developing vaccine adjuvants and drug products from preclinical studies through Phase III clinical trials with line of sight to commercialization. We ensure robust composition, primary packaging, and process development through deep fundamental understanding and characterization such that the process is scalable without compromising safety, efficacy, or stability. During development, we leverage smart experimental design, cutting edge analytical tools, and statistical/predictive approaches to inform formulation and process development. Our team enables the translation of vaccine preclinical candidates from concepts into robust commercial drug products.
Primary responsibilities of the role include design, execution, and documentation of experiments to develop stable formulations and robust manufacturing processes for preclinical and clinical supply production and to scale-up these processes to the pilot plant and commercial space. The successful candidate will be expected to work independently in a hands-on, dynamic laboratory environment engaged in development activities while also working collaboratively within the group, across functional areas, and with external partners.
Active strategic and technical leadership on program development teams will be required. Strong communication skills are expected to clearly communicate data and conclusions verbally, through written documents and reports, and technical presentations. Proven facilitative leadership and communication skills are essential to effectively lead matrix teams and manage expectations of stakeholders as part of our stage-gate process used to manage the development of new products. The role will also entail supporting or leading teams to advance areas such as science and technology innovation, business process improvement, and clinical manufacturing capability build.
Successful candidates are motivated to excel, willing to take initiative, have a strong desire to learn and contribute, and actively mentor less experienced scientists. Senior colleagues in Vaccine Drug Product Development have strong external scientific networks to help us maintain an awareness of industry challenges, trends, and opportunities. Successful candidates will have a track record of external publication, patenting, and presentations.
Required Experience and Skills
Ph.D. in chemical/biochemical engineering, pharmaceutical sciences, chemistry, biochemistry, or related discipline with 8 years of relevant industrial experience; an M.S. degree in a similar field with 10 years of relevant experience; or a B.S. degree in a similar field with 12 years of relevant experience.
Proven written and verbal communication skills
Ability to prioritize, plan, and execute work with limited guidance
Ability to work in a dynamic and fast-paced team environment
Demonstrated facilitative leadership and influencing skills
Hands on laboratory skills
Experience developing vaccine adjuvant and/or vaccine drug product processes, including advanced knowledge of key unit operations (freeze/thaw, formulation, mixing, filtration, filling, stoppering, etc.)
Understanding of vaccine adjuvant and/or drug product quality attributes, specifications, characterization techniques, and product vulnerabilities and mitigation strategies
Experience with engineering principles used in process development and process scale up/scale down
Experience with technical transfer of processes from lab to pilot plant and/or commercial sites including the use of risk assessment tools
Track record of difficult technical problem solving
Ability to develop and implement new methods/processes
Experience with GMP manufacturing of clinical supplies
Experience with use of statistical principles to understand, predict, and communicate process robustness
Experience with root cause analysis and investigations (FMEA, fishbone, etc.)
Experience authoring regulatory filings for sterile dosage forms (adjuvants and/or DP)
Experience responding to regulatory questions related to drug products
Experience, desire, and a track record of effective mentorship of less experienced scientists towards timebound goals
Desired Experience and Skills
Experience with sterile product manufacturing and aseptic technique
Experience with colloidal systems and characterization of colloids including emulsions
Familiar with ISO, CFR, ICH, and USP guidelines as they relate to sterile products
Familiar with Quality by Design (QbD) principles and have experience applying the QbD tools and principles to products in development
Experience with process modeling
Experience with liquid and lyophilized drug product formulation development
Understanding of compliance and regulatory issues for sterile injectable products manufactured by aseptic processing
Experience with direct people management
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
10%Flexible Work Arrangements:
Not ApplicableShift:
1st - DayValid Driving License:
NoHazardous Material(s):
n/aOfficial account of Jobstore.
Job Description
Vaccine Drug Product Development (VDPD), a part of our company's Research Laboratories, is seeking an Associate Principal Scientist to join our department in West Point, PA. Our mission is to develop novel vaccine drug products that will profoundly improve global human health—directly building from our company's 50+ year legacy as pioneers in the discovery, development, and manufacturing of novel vaccines to eliminate disease. Our department is responsible for developing vaccine adjuvants and drug products from preclinical studies through Phase III clinical trials with line of sight to commercialization. We ensure robust composition, primary packaging, and process development through deep fundamental understanding and characterization such that the process is scalable without compromising safety, efficacy, or stability. During development, we leverage smart experimental design, cutting edge analytical tools, and statistical/predictive approaches to inform formulation and process development. Our team enables the translation of vaccine preclinical candidates from concepts into robust commercial drug products.
Primary responsibilities of the role include design, execution, and documentation of experiments to develop stable formulations and robust manufacturing processes for preclinical and clinical supply production and to scale-up these processes to the pilot plant and commercial space. The successful candidate will be expected to work independently in a hands-on, dynamic laboratory environment engaged in development activities while also working collaboratively within the group, across functional areas, and with external partners.
Active strategic and technical leadership on program development teams will be required. Strong communication skills are expected to clearly communicate data and conclusions verbally, through written documents and reports, and technical presentations. Proven facilitative leadership and communication skills are essential to effectively lead matrix teams and manage expectations of stakeholders as part of our stage-gate process used to manage the development of new products. The role will also entail supporting or leading teams to advance areas such as science and technology innovation, business process improvement, and clinical manufacturing capability build.
Successful candidates are motivated to excel, willing to take initiative, have a strong desire to learn and contribute, and actively mentor less experienced scientists. Senior colleagues in Vaccine Drug Product Development have strong external scientific networks to help us maintain an awareness of industry challenges, trends, and opportunities. Successful candidates will have a track record of external publication, patenting, and presentations.
Required Experience and Skills
Ph.D. in chemical/biochemical engineering, pharmaceutical sciences, chemistry, biochemistry, or related discipline with 4 years of relevant industrial experience; an M.S. degree in a similar field with 6 years of relevant experience; or a B.S. degree in a similar field with 8 years of relevant experience.
Proven written and verbal communication skills
Ability to prioritize, plan, and execute work with limited guidance
Ability to work in a dynamic and fast-paced team environment
Demonstrated facilitative leadership and influencing skills
Hands on laboratory skills
Experience developing vaccine adjuvant and/or vaccine drug product processes, including advanced knowledge of key unit operations (freeze/thaw, formulation, mixing, filtration, filling, stoppering, etc.)
Understanding of vaccine adjuvant and/or drug product quality attributes, specifications, characterization techniques, and product vulnerabilities and mitigation strategies
Experience with engineering principles used in process development and process scale up/scale down
Experience with technical transfer of processes from lab to pilot plant and/or commercial sites including the use of risk assessment tools
Track record of difficult technical problem solving
Ability to develop and implement new methods/processes
Experience with GMP manufacturing of clinical supplies
Experience with use of statistical principles to understand, predict, and communicate process robustness
Experience with root cause analysis and investigations (FMEA, fishbone, etc.)
Experience authoring regulatory filings for sterile dosage forms (adjuvants and/or DP)
Experience responding to regulatory questions related to drug products
Experience, desire, and a track record of effective mentorship of less experienced scientists towards timebound goals
Desired Experience and Skills
Experience with sterile product manufacturing and aseptic technique
Experience with colloidal systems and characterization of colloids including emulsions
Familiar with ISO, CFR, ICH, and USP guidelines as they relate to sterile products
Familiar with Quality by Design (QbD) principles and have experience applying the QbD tools and principles to products in development
Experience with process modeling
Experience with liquid and lyophilized drug product formulation development
Understanding of compliance and regulatory issues for sterile injectable products manufactured by aseptic processing
Experience with direct people management
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
10%Flexible Work Arrangements:
Not ApplicableShift:
1st - DayValid Driving License:
NoHazardous Material(s):
n/aOfficial account of Jobstore.
Job Description
Vaccine Drug Product Development (VDPD), a part of our company's Research Laboratories, is seeking a Senior Scientist to join our department in West Point, PA. Our mission is to develop novel vaccine drug products that will profoundly improve global human health—directly building from our company's 50+ year legacy as pioneers in the discovery, development, and manufacturing of novel vaccines to eliminate disease. Our department is responsible for developing vaccine adjuvants and drug products from preclinical studies through Phase III clinical trials with line of sight to commercialization. We ensure robust composition, primary packaging, and process development through deep fundamental understanding and characterization such that the process is scalable without compromising safety, efficacy, or stability. During development, we leverage smart experimental design, cutting edge analytical tools, and statistical/predictive approaches to inform formulation and process development. Our team enables the translation of vaccine preclinical candidates from concepts into robust commercial drug products.
Primary responsibilities of the role include design, execution, and documentation of experiments to develop stable formulations and robust manufacturing processes for preclinical and clinical supply production and to scale-up these processes to the pilot plant and commercial space. The successful candidate will be expected to work independently in a hands-on, dynamic laboratory environment engaged in development activities while also working collaboratively within the group, across functional areas, and with external partners.
Active strategic and technical leadership on program development teams will be required. Strong communication skills are expected to clearly communicate data and conclusions verbally, through written documents and reports, and technical presentations. The role will also entail supporting or leading teams to advance areas such as science and technology innovation, business process improvement, and clinical manufacturing capability build.
Successful candidates are motivated to excel, willing to take initiative, have a strong desire to learn and contribute, and actively mentor less experienced scientists. Senior colleagues in Vaccine Drug Product Development have strong external scientific networks to help us maintain an awareness of industry challenges, trends, and opportunities. Successful candidates will have a track record of external publication, patenting, and presentations.
Required Experience and Skills
Ph.D. in chemical/biochemical engineering, pharmaceutical sciences, chemistry, biochemistry, or related discipline with 0-2 years of relevant industrial experience; an M.S. degree in a similar field with 4 years of relevant experience; or a B.S. degree in a similar field with 6 years of relevant experience.
Proven written and verbal communication skills
Ability to prioritize, plan, and execute work with limited guidance
Ability to work in a dynamic and fast-paced team environment
Demonstrated facilitative leadership and influencing skills
Hands on laboratory skills
Experience developing vaccine adjuvant and/or vaccine drug product processes, including advanced knowledge of key unit operations (freeze/thaw, formulation, mixing, filtration, filling, stoppering, etc.)
Familiar with vaccine adjuvant and/or drug product quality attributes, specifications, characterization techniques, and product vulnerabilities and mitigation strategies
Experience with engineering principles used in process development and process scale up/scale down
Track record of difficult technical problem solving
Ability to develop and implement new methods/processes
Familiar with use of statistical principles to understand, predict, and communicate process robustness
Familiar with root cause analysis and investigations (FMEA, fishbone, etc.)
Experience, desire, and a track record of effective mentorship of less experienced scientists towards timebound goals
Desired Experience and Skills
Experience with technical transfer of processes from lab to pilot plant and/or commercial sites including the use of risk assessment tools
Experience with GMP manufacturing of clinical supplies
Experience with sterile product manufacturing and aseptic technique
Experience with colloidal systems and characterization of colloids including emulsions
Familiar with ISO, CFR, ICH, and USP guidelines as they relate to sterile products
Familiar with Quality by Design (QbD) principles and have experience applying the QbD tools and principles to products in development
Experience with process modeling
Experience with liquid and lyophilized drug product formulation development
Experience authoring regulatory filings for sterile dosage forms (adjuvants and/or DP)
Experience responding to regulatory questions related to drug products
Understanding of compliance and regulatory issues for sterile injectable products manufactured by aseptic processing
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
No relocationVISA Sponsorship:
NoTravel Requirements:
10%Flexible Work Arrangements:
Not ApplicableShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
n/aOfficial account of Jobstore.
Graco manufactures and markets premium equipment to move, measure, control, dispense and spray a wide variety of fluid and powder materials. What does that mean? Well, we pump peanut butter into your jar, and the oil in your car. We glue the soles of your shoes, the glass in your windows and the screen on your phone. We spray the finish on your vehicle, coatings on your pills, the paint on your house and texture on your walls. Graco is part of your daily life.
PURPOSE OF JOB:
Provide leadership of product development projects from a procurement perspective. Management of day-to-day procurement tasks/reporting including: communication with designers/contractors/vendors/suppliers to deliver on-time and cost-competitive; products, project timelines, milestones, deadlines and documentation of product costs, providing a smooth transition from development into production. Work closely with commodity managers, engineers, and suppliers to reduce the product development cycle while improving the value of purchased components. Communicate project timing to buyers and suppliers.
SCOPE:
Rotational supply chain, procurement and sourcing, single point of contact, project leadership role for the support of new product development initiatives and capital equipment purchases for assigned Graco business units/divisions.
PRINCIPAL ACTIVITIES/DUTIES:
Identify and manage the sourcing and procurement resource requirements of multiple New Product design teams and Capital Equipment Requirements. Creates and executes project work plans and revises as appropriate to meet changing needs and requirements. Initiate early supplier involvement and commodity management engagement – “kick-off meetings” with engineering, purchasing, and the supplier to drive shorter product development time. Manage print reviews with engineers and suppliers for all tooled parts. Drive standardization of components in development and supplier reduction. Communicate the need for new suppliers/commodities when necessary to Purchasing Department. Responsible for coordinating quoting with buyers, using eoq’s developed with the planner. Provide new product update meetings for the Purchasing Department. This meeting will cover markets, timing, forecasted volumes, etc. Coordinate all engineering requisitions for tooling, prototype, and field test parts. Ensure that Oracle ERP system is updated accordingly. Communicate tooling lead time and status of all parts, tooled or standard, to the engineering project manager. Responsible for the purchasing portion of Phase Exit reviews, including confirmation of supplier selection and approval, first article completion, and accurate standard costs. Responsible for make vs. buy analysis, input into eoq’s and pricing, and completion of first articles prior to RFS. Other duties as assigned by management.
POSITION REQUIREMENTS:
Essential:
Desirable:
#LI-AI1
Power to Be
At Graco, the Power to Be means providing the support, resources and freedom to pave your own way. Bring your unique attributes to the table, along with a commitment to being your best self, and you can be a part of a culture that rewards effort, celebrates uniqueness, and gives you the tools you need to succeed and become your best, fullest self along the way. Our culture empowers employees to chart their own career path. Our managers provide support and opportunities while offering freedom for employees to find their own Power to Be. Whether you decide to move up within the same department or expand to another cross-functional group, you will gain the well-rounded experience to succeed on your own terms.
Graco has excellent opportunities available to individuals who want to be part of a fast-moving, growing company that is committed to quality, innovation and solving fluid handling problems for our customers. Graco is proud to be named a Best Place to Work by Fortune Magazine in 2016, 2018, 2019, 2021 & 2022. Graco offers attractive compensation, benefits and career development opportunities. Graco’s comprehensive benefits include medical, dental, stock purchase plan, 401(k), tuition reimbursement and more.
Our company uses E-Verify to confirm the employment and eligibility of all newly hired employees. To learn more about E-Verify, including your rights and responsibilities, please visit www.dhs.gov/E-Verify.
Proven Quality. Leading Technology. Launch your career with Graco!
Official account of Jobstore.
Manufacturing jobs are involved in developing new products with raw materials or components. These jobs are located in a factory, plant or mill. Manufacturing and production are comprised of technicians, production manager, production planner, production supervisor, assembler, operators, assemblers, machinists, fabricators, printing, quality control, tailors, welders, water treatment and woodworkers.
The role of welder is to cut and join metals at facilities. Responsibilities include reading measurements to plan layout, determine the appropriate welding equipment, set up components for welding according to specifications, align components using clamp pieces, repair machinery, inspecting welded structure to find flaws and maintain equipment in a condition that does not compromise safety.
The role of production engineer is to oversee the production of goods in various industries at factories. Responsibilities include handling budget, ensuring project deadlines are met, analysis of the data found in charts, analysis of operational issues, provide team with technical support and training.
The role of production manager is to organise and oversee the manufacturing of goods. Responsibilities include liaising with other managers to formulate objectives, prepare budgets, organise workflow to meet specifications, monitor production to resolve issues, evaluate the performance of production personnel, approve maintenance work, enforce health and safety regulations.
The role of production planner is to organise production according to demand and quality standards. Responsibilities include plan operations to ensure maximum performance, assign workers to particular production operations, schedule shift according to production needs, monitor jobs to ensure they will finish on time, address issues when they arise aiming for minimum disruption and keep paperwork organised.
The role of operator is to set up, maintain and operate machinery. Responsibilities include feed raw material to semi-automated machines, inspect parts with precision, test operations of machines periodically, fix issues that might occur during the shift, check output to spot any machine-related mistakes, keep records of products and maintain activity logs.
The role of maintenance technician is to manage maintenance in the facilities to ensure the smooth running of upkeep or repair operations, Responsibilities include inspect facilities periodically to determine problems, prepare weekly maintenance schedules, recruit maintenance technicians, supervise tradesmen during installations,ensure adherence to quality standards, health and safety regulations.
The role of technician is to deliver the desired customer service experience. Responsibilities include providing customer support during field visits, tie workflow to schedule, manage all on site installations, diagnose technical problems, produce detailed service reports, document process, follow all company’s filed procedures and protocols.
The role of OSH officer is to facilitate compliance with occupational health and safety(OHS) guidelines. Responsibilities include supporting the development of OHS policies, advise on various safety-related topics, conduct a risk assessment, review existing policies, organise OHS training of employees, prepare reports on occurrences and provide statistical information to upper management.
The role R&D engineer is to conduct research and development activities for an organisation. Responsibilities include summarise research results, assess the scope of research projects, ensure projects are within budget, develop technical documentation for all projects, take leadership of projects in development, collaborate with engineers and developers to create product designs with marketing teams to develop sales plans for future products.
The role of boilerman is to maintain heating systems in large buildings in the boiler, engine and mechanical rooms. Responsibilities include handling hot water heating systems, perform routine maintenance, keeping safety at the forefront when attending to problems, record service data in logs and follow strict safety procedures during work.
The role of CNC machinist is to use computer numerically controlled(CNC) machinery safely and accurately to perform a variety of functions. Responsibilities include understand specifications of the task at hand, translate instructions into cnc programming so the machines can perform the correct function, prepare raw materials, prepare test runs for cnc mills and maintain machinery daily to ensure functionality.
The role of machine operator is to set up, maintain and operate machinery. Responsibilities include set up machines to start a production cycle, adjust machine settings, feed materials to semi-automated machines, test operations of machines periodically, fix issues that might occur during the shift, check output to spot any machine-related flaws and maintain activity logs.
The role of storekeeper is to manage the maintenance of a department’s storeroom which includes stocking of operational materials and supplies. Responsibilities include keeping records to maintain inventory control, oversees mail handling, operate simple office machines, perform related and peripheral site-specific duties as required.